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Author

Patrick Descombes

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Open access Oct 2026

Association mapping and genome prediction reveal a complex genetic architecture for resistance to black and frosty pod rot in cacao (Theobroma cacao L.) populations

Abstract Cacao (Theobroma cacao L.) production is severely constrained by black pod rot (BPR) and frosty pod rot (FPR), two major diseases that cause substantial yield losses across the tropics. Breeding for disease resistance remains challenging due to long generation intervals and the complex genetic control of disea...

Elisa Jacquotte, James A. Holzwarth, Ana Zotta Mota et al. · 0 citations
Open access Aug 2026

A scalable microarrayed organoid platform for precision modeling of intestinal epithelial damage and recovery.

Chronic inflammatory bowel diseases (IBDs), including Crohn's disease, are characterized by relapsing-remitting intestinal inflammation associated with epithelial barrier dysfunction. Existing preclinical models of IBD have limited capacity to quantitatively capture dynamic epithelial damage and recovery, which hinders...

Marine Meyer, A. Roch, Juliane Dervaux et al. · 0 citations

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