Refining Allostatic Load Measurement: Mortality Associations of an Empirically Derived Three-Component Score in the Women's Health Initiative.
Allostatic load (AL) is a multisystem index of physiological dysregulation due to chronic stress. Although widely applied, its operationalization remains inconsistent, limiting reproducibility and equity. Streamlined indices based on common biomarkers may enhance feasibility across settings. Using data from 150 293 pos...