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Author

Paul A. Heidenreich

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Open access Sep 2026

Gut microbiome shifts in chronic systolic heart failure are associated with disease severity and clinical improvement

The contribution of the gut microbiome to chronic heart failure (HF) remains poorly defined. We performed integrated microbiome and host multi-omic profiling of adults with chronic systolic HF due to nonischemic cardiomyopathy (n = 59) and healthy participants (n = 50), including longitudinal sampling in some cases. He...

Petra Mamic, Han-Duo Shi, Wen-Yu Zhou et al. · 0 citations
Open access Sep 2026

Automated Aortic Valve Calcification Scoring: Multicenter External Validation of a Deep Learning Algorithm.

BACKGROUND Aortic valve calcification (AVC) quantification is a guideline-recommended imaging biomarker for aortic stenosis (AS) severity and progression yet remains underreported on routine chest computed tomography (CT). With nearly 20 million nongated chest CTs performed annually in the United States, automated AVC...

Jimmy Zheng, Eren Alkan, Aniruddha K. Deshpande et al. · 0 citations

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