Author

P. D. Olinares

2 papers indexed here

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Open access Oct 2026

Conserved mycobacteriophage protein uses structural mimicry to displace host initiation factors

Compact viral genomes encode sophisticated strategies to reprogram host gene expression, often by co-opting rather than replacing RNA polymerase. How bacteriophages achieve such control in Mycobacteria remains largely unknown. Here, time-resolved interaction proteomics of mycobacteriophage D29 infection identifies a co...

David R. Parker, Shrestha Ghosh, Adela Dujiskova et al. · bioRxiv · 0 citations

Open access Aug 2026

Structural and biophysical characterization of Mycobacterium tuberculosis DciA reveals functional convergence in DnaB helicase recognition

In bacteria, DnaB replicative helicases are essential for unwinding genomic DNA to provide the single‐stranded templates required for replication. The recruitment of the hexameric DnaB helicase to the origin of replication is mediated by distinct mechanisms that rely on specialized factors known as helicase loaders. Th...

Daniele Mazzoletti, Andrea Garavaglia, Hayden Fisher et al. · Protein Science · 0 citations