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Author

Paula Martínez-Cenalmor

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Open access Aug 2026

Vimentin remodeling in response to oxidants and electrophiles is modulated by pH

Vimentin is critical for cell mechanosensing, cytoskeletal cross-talk, and stress responses and is finely tuned by posttranslational modifications. Vimentin single cysteine, C328, is a modification hotspot, essential for filament remodeling by oxidants and electrophiles. With a pKa near physiological pH, C328 reactivit...

Alma E. Martínez, Paula Martínez-Cenalmor, Patricia González-Jiménez et al. · 1 citation
Open access Aug 2026

Mimicking two posttranslational modifications associated with oxidative stress affords phase separation of vimentin

This work aimed to generate vimentin condensates by inserting mutations mimicking posttranslational modifications associated with oxidative stress by introducing phosphomimetic residues at certain single vimentin glycosylation and/or phosphorylation sites, and suggested a modulatory role of glycosylation/phosphorylatio...

Diego Moneo-Corcuera, Paula Martínez-Cenalmor, Alma E. Martínez et al. · 0 citations

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