Quality by Design (QbD) Based Optimization and Validation of an RP-HPLC Method for Simultaneous Analysis of Multicomponent Topical Cream
This study reports the development and validation of a rapid, specific, and robust Reverse-Phase High-Performance Liquid Chromatography (RP-HPLC) method for the simultaneous estimation of Ofloxacin (OFL), Ornidazole (ORN), Itraconazole (ITR), and Clobetasol (CLO) in a cream formulation. A systematic Quality by Design (...