Open access
Aug 2026
Selective quality control of mistargeted mitochondrial proteins at the endoplasmic reticulum
In eukaryotic cells, the function of each organelle depends on its unique protein composition. Protein targeting errors threaten organelle identity and function, yet how mistargeting errors are detected and resolved remains poorly understood. Here, we show that mitochondrial import stress drives widespread rerouting of...
Y. Tsuchiya, Nikita Sergejevs, M. E. Dueñas et al.
· bioRxiv · 0 citations