Pei-Chen Lu

Haptoglobin is associated with nocturnal blood pressure non-dipping in children with chronic kidney disease

Blood pressure (BP) follows a circadian rhythm that depends partly on endothelial nitric oxide (NO) bioavailability. Cell-free hemoglobin rapidly scavenges NO, and haptoglobin functions as a capacity-limited plasma buffer facilitating hemoglobin clearance. Whether reduced circulating haptoglobin contributes to ci...