Alzheimer’s disease (AD), the most common cause of dementia in older adults, is characterized by progressive cognitive decline, synaptic dysfunction, and neuronal loss. Among the multifactorial mechanisms implicated in AD, reciprocal interactions between brain-derived neurotrophic factor (BDNF) and amyloid-β (Aβ) have...
Fangfang Liu, Yuanmao Huang, Aiping Wang et al.· Frontiers in Molecular Neuro...· 0 citations
Key approaches targeting DNA repair deficiency, immune regulation, oncogenic signaling pathways, and antigen-directed therapies are highlighted, and their clinical development and application are discussed.
Hui-Fang Cheng, Yanmei Chen, Pei-Yan Liu et al.· Acta Pharmacologica Sinica· 0 citations
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