Electrochemical Cytosensor with Dual-Site Recognition Fabricated by In Situ Catalase-Encapsulated Metal-Organic Frameworks for Isolation and Detection of Circulating Tumor Cells in Whole Blood.
Circulating tumor cells (CTCs) are critical biomarkers for cancer prognosis and treatment monitoring, yet their detection remains challenging due to low abundance and phenotypic heterogeneity. Herein, we developed a dual-aptamer-conjugated electrochemical cytosensor using an in situ catalase (CAT)-encapsulated nanozyme...