Author

Peixi Zhao

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Open access Aug 2026

Fuzheng Huayu Jiedu formula induces ferroptosis associated with p53/HO-1/GPX4 axis and inhibits malignant progression in A549 lung cancer cells

Fuzheng Huayu Jiedu Formula (FHJF) is a traditional Chinese herbal formula with reported anti-tumor properties. However, its mechanism against non-small cell lung cancer (NSCLC) remains unclear. In the present study, we employed human lung adenocarcinoma A549 cells as an in vitro model. Cell proliferation and migrati...

Wei Chen, Yi Cui, Le Han et al. · Scientific Reports · 0 citations

Open access Jul 2026

Quercetin induces ferroptosis in ovarian cancer by suppressing the NRF2/HO‑1/GPX4 axis and increasing the efficacy of cisplatin.

Quercetin (Quer), a naturally occurring flavonoid, has received significant attention because of its antitumor effectiveness and ability to synergistically enhance chemotherapy-induced effects by counteracting drug resistance. Ovarian cancer (OC) is a highly aggressive malignancy characterized by frequent chemoresistan...

Hui Li, Zhaoxuan Liu, Hailong Shi et al. · Biochemical Pharmacology · 0 citations