Open access
Sep 2026
High TG/low HDL-C ratio–mimetic lipid stress drives diabetic atherosclerotic endothelial–macrophage dysfunction through glycocalyx disruption and CD36/ABCA1 imbalance
A high triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratio is strongly associated with insulin resistance and atherosclerotic cardiovascular risk, but the cellular mechanisms linking this lipid imbalance to vascular injury remain incompletely defined. This study established a combined hyperglycemic/high...
Le-Chang Bi, Wen Zhao, Ming-Jing Lu et al.
· Journal of Molecular Histolo... · 0 citations