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Peng-Fei Ren

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Open access Sep 2026

Dietary alpha-lipoic acid supplementation alleviates high-fat diet-induced hepatic steatosis and inflammation by remodeling the gut microbiota and restoring the primary bile acid pool.

BACKGROUND Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent global health concern with limited therapeutic options. Alpha-lipoic acid (ALA), a naturally occurring organosulfur compound with potent antioxidant activity, shows hepatoprotective potential, but its mechanisms along the gut-liv...

Peng-Fei Ren, Hui Qi, Bi-Qian Wei et al. · 0 citations

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