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Author

Peng-Fei Ren

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Review Open access Aug 2026

Persistent IFN-I signaling associated with the HIV-1 reservoir fuels immune exhaustion and reveals therapeutic targets

This review systematically examines the molecular and cellular mechanisms by which the HIV-1 reservoir fuels immune exhaustion through the IFN-I signaling pathway, providing a theoretical framework for the development of novel therapeutic strategies aimed at reservoir elimination or reversal of immune exhaustion.

Zhi-Hui Zhang, Peng-Fei Ren, Meng Deng et al. · 0 citations

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