Peng-Fei Wang

An IS26-assembled three-module chimeric plasmid co-localizing blaNDM–1 and blaKPC–2 undergoes post-transfer rearrangement in Klebsiella pneumoniae

Introduction Carbapenem-resistant Klebsiella pneumoniae (CRKP) poses a severe global public health threat, driven largely by plasmid-borne carbapenemase genes such as blaNDM–1 and blaKPC–2. Although CRKP strains co-producing multiple carbapenemases are increasingly reported, the co-localization of these genes on a sing...