Open access
Oct 2026
Eggshell-Templated Mn-Doped Hydroxyapatite Composite Scaffold: Coupling ROS Scavenging with Piezo1 Activation for Bone Regeneration
The treatment of critical-sized bone defects remains challenging due to immune microenvironment dysregulation characterized by excessive ROS, persistent inflammation, and apoptosis, which impede tissue regeneration. Conventional biomaterials often overlook the unique structure and composition of natural materials. He...
Meng-Qi Zhao, Jing-Yang Cheng, Hui Zheng et al.
· Regenerative Biomaterials · 0 citations