Open access
Oct 2026
Sanguinarine Reduces Conjugative Transfer of mcr-1-Positive Plasmids in Escherichia coli
Background/Objectives: IncI2 and IncX4 plasmids are important vehicles for dissemination of the mobile colistin resistance gene mcr-1. We evaluated whether sanguinarine (SA) reduces conjugative transfer of these two mcr-1-carrying plasmid types and examined biological changes accompanying the transfer phenotype. Method...
Xue-Yang Wang, Jun-Feng Zhang, Zhan-Kui Lin et al.
· Antibiotics · 0 citations