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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Peng Li

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2 papers indexed here

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Open access Sep 2026

HOTAIR Promotes Prostate Cancer Progression by facilitating CDK9-Pol II Association and Transcriptional Elongation

Previous research has predominantly focused on the regulatory role of lncRNA HOTAIR in gene silencing by interacting with the Polycomb repressive complex 2 (PRC2), but its direct role as a transcriptional activator remains less well characterized. Here, our study reveals a novel regulatory mechanism of HOTAIR, which fa...

Yu-Yang Qian, Bo Wang, Guang-Song Su et al. · 0 citations
Open access Sep 2026

A prostate cancer-specific super-enhancer at 1q42.3 regulates the CAPN2 and KRT19.

Genetic susceptibility plays an essential role in prostate cancer (PCa) risk, while the functional mechanisms underlying several classic risk loci remain largely uncharacterized. Here, we identified a PCa specific super-enhancer within 1q42.3 locus, termed NR125945-SE, which resides within a previously reported PCa sus...

Zhen-Hao Zhao, Yun-Long Bai, Qin Wang et al. · 0 citations

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