Transcriptomics-informed systems toxicology prioritizes candidate links between endocrine-disrupting chemicals and chronic kidney disease.
A transcriptomics-informed systems toxicology workflow to prioritize CKD-relevant candidate genes associated with predicted human protein targets of 12 selected representative EDCs compiled from ChEMBL, SwissTargetPrediction and PharmMapper, which prioritizes an externally evaluated FOS/MDK diagnostic-candidate panel a...