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Open access Aug 2026

Integrated Transcriptomic and DNA Methylation Analysis Reveals ITGB2-Mediated Immune Dysregulation in Polycystic Ovary Syndrome and Its Modulation by Rutin.

OBJECTIVES To identify immune-related molecular targets in polycystic ovary syndrome (PCOS) and evaluate the role of integrin beta-2 (ITGB2) and the potential modulation by rutin. METHODS Follicular fluid cytokines from 30 women with PCOS and 30 control women were profiled. Transcriptomic (GSE34526) and DNA methylati...

Peng Yi, Ying-Ying Cao, Yan-Ru Zhou et al. · 0 citations

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