Advances in nano drug delivery systems for targeted microglia modulation in ischemic stroke treatment
Ischemic stroke (IS) progression is closely linked to neuroinflammation from microglial polarization imbalance. Its precise modulation, however, is limited by poor blood–brain barrier (BBB) penetration, low spatiotemporal accuracy, and systemic off-target effects. Nano drug delivery systems (NDDS) offer a promising...