Author

Perry B. M. Leung

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Open access Sep 2026

The associations of adverse childhood experiences and resilience with psychopathology and addictive behaviour in Chinese patients with substance use disorder.

BACKGROUND Adverse-childhood-experiences (ACEs) are prevalent in substance-use-disorder (SUD) but show complex interplay with resilience, psychopathology and addictive-behaviour. The stress-diathesis model predicts that ACEs can induce psychopathologies and undermine resilience, leading to addictive-behaviour. However,...

Yolanda Y. C. Tsang, Michelle Y. Deng, Raisie W. K. Wong et al. · Drug and Alcohol Dependence · 0 citations

Open access Aug 2026

Integrating biological pathway polygenic scores and trauma in psychosis: findings from the EU-GEI study

Findings provide proof-of-concept for the utility of pPGSs in psychiatric research, suggesting both genetic contributions to trauma exposure and GxE effects on psychosis risk, as well as supporting pathway-specific contributions beyond general polygenic risk.

G. Trotta, I. Austin-Zimmerman, E. Spinazzola et al. · Translational Psychiatry · 0 citations