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Author

Pete A. Williams

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2 papers indexed here

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Open access Sep 2026

Functional and structural analysis in relation to age at onset of Leber hereditary optic neuropathy: a Swedish cohort.

PURPOSE To evaluate macular ganglion cell complex (GCC) thickness, retinal vessel tortuosity, visual function, and treatment effects in chronic Leber hereditary optic neuropathy (LHON) stratified by age at onset. METHODS Thirty-one chronic LHON subjects from the Swedish LHON registry were enrolled and grouped by age...

J. Hedström, Marie Nilsson, Sofia Fagerstrom et al. · 0 citations
Open access Oct 2026

Development of Organocatalytic Switches of OGG1 that Protect Mitochondria under Oxidative Stress

Mitochondrial dysfunction is a major component of neurodegeneration. The mitochondrial genome is prone to oxidative damage, and repair proteins are important to maintain mitochondrial DNA integrity. OGG1 initiates base excision repair of oxidative DNA lesions in both nuclear and mitochondrial genomes. While inhibitor...

Maeve Long, James R. Tribble, Rahul Upadhyay et al. · 0 citations

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