Open access
Jul 2026
Sulfotransferase signaling sustains fibroblast identity and antagonizes therapeutic cardiac reprogramming
Differentiated cells maintain their identity through active mechanisms that suppress alternative cell fates, but disrupting these barriers can enhance direct reprogramming for organ repair. Among the regulators of cell fate stability, glycosylation-associated genes have emerged as barriers to cardiac reprogramming. Her...
Michaela R. Romero, S. Murphy, Yuzhu Chang et al.
· Nature Communications · 0 citations