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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Philip Moheno

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2 papers indexed here

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#graph neural networks Sep 2026

Abstract B002: Computational Discovery of Evolutionary Synthetic Lethality Networks for Personalized Gene Therapy and Small-Molecule Design in Treatment-Resistant Pediatric High-Grade Glioma

An integrative computational framework is developed to reconstruct resistance evolution, identify state-specific therapeutic vulnerabilities, and design personalized gene therapy and blood-brain barrier (BBB)-penetrant small-molecule therapeutics targeting treatment-resistant pediatric glioma.

Shivi Kumar, Philip Moheno, Sweta Gupta · 0 citations
#graph neural networks Sep 2026

Abstract B004: Targeting Transient Cell-State Dependencies in Glioblastoma Through Single-Cell Evolutionary Modeling and Structure-Based Drug Design

A computational framework is presented that reconstructs the evolutionary trajectory of glioblastoma cells under treatment pressure and uses that trajectory to identify druggable targets that exist only transiently, during state transition, to isolate signaling dependencies that appear specifically during the resistanc...

Shivi Kumar, Philip Moheno, Sweta Gupta · 0 citations

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