Open access
Oct 2026
A pro-inflammatory effector-memory T cell program links peripheral EBV priming to CNS autoimmunity
T and B cell–mediated immunosurveillance of the central nervous system (CNS) can become maladaptive in multiple sclerosis (MS). Epstein–Barr virus (EBV) is a likely driver of MS, yet how exactly EBV-specific T cells contribute remains unclear. We generated an antigen-resolved atlas of blood and cerebrospinal fluid (CSF...
N. Kristensen, T. Tsaktanis, S. Frischholz et al.
· bioRxiv · 0 citations