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Author

Philippe Roingeard

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2 papers indexed here

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Open access Sep 2026

Functional redundancy, complementation, and cross-talk between CH25h and IFITM3 in infection and in IFITM3 trafficking and secretion

ABSTRACT Type I interferon induces multiple protein effectors to inhibit viral replication. Among these, the interferon-induced transmembrane protein (IFITM3) and the cholesterol-25-hydroxylase (CH25h) converge on the inhibition of viral entry by altering the behavior of membranes. Here, we dissect the functional and m...

Yu-Xin Song, Ting-Ting Xia, Charlène Martin et al. · 0 citations
Open access Jul 2026

MITD1 restricts HIV-1 release by targeting ESCRT-III proteins.

It is shown that MITD1, a cell type-specific interferon-stimulated gene, is a potent inhibitor of ESCRT-dependent HIV-1 budding, and is established as an interferon-stimulated restriction factor that limits HIV-1 egress by perturbing ESCRT-III assembly.

Jim Zoladek, Marion Cannac, Claire Lacouture et al. · 0 citations

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