A single-cell perspective on polyethylene microplastic toxicity: linking fibroblast reprogramming to immune microenvironment alterations in the lung.
BACKGROUND Microplastics represent ubiquitous and persistent environmental contaminants, with growing evidence of their accumulation in human tissues including the lung. Chronic pulmonary exposure has been associated with tissue damage, fibrotic remodeling, and immune dysregulation; however, a systematic understanding...