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Pia Jensen

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Open access Aug 2026

STEP-PTMs: Sequential TMT-based Enrichment and Profiling of Post-Translational Modifications

Application of STEP-PTM to TMT16-plex cerebral brain organoids enabled the quantification of 10,413 proteins, 2,969 metabolites, 19,655 phosphopeptides, 28,876 peptides containing reversibly modified cysteines, 9,723 peptides containing free cysteines, 1,716 intact sialylated N-linked glycopeptides and 771 lysine-acety...

Lucrezia Criscuolo, S. B. Elmkvist, Arkadiusz Nawrocki et al. · 0 citations
Jul 2026

Proteomic and Phosphoproteomic Characterization of Disease-Associated Alterations in Nerve Terminals and Protein Inclusions of Alzheimer's Disease Patients.

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by synaptic dysfunction, protein aggregation, and widespread molecular alterations in the brain. In this study, we applied quantitative mass spectrometry-based proteomics and phosphoproteomics to characterize synaptosomes and sarkosyl-in...

S. B. Elmkvist, Camilla Thygesen, Pia Jensen et al. · 0 citations

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