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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Piaopiao Cai

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Jul 2026

Lactate-associated H3K18 lactylation is involved in IGF2BP2-mediated MARCKSL1 mRNA stabilization and inflammatory signaling in LPS-induced acute lung injury.

N6-methyladenosine (m6A) RNA modification regulates pulmonary inflammation, yet the precise function of the m6A reader IGF2BP2 in acute lung injury (ALI) remains elusive. Here, we reveal that IGF2BP2 and global m6A levels are significantly upregulated in lipopolysaccharide (LPS)-induced ALI. Prophylactic genetic silenc...

Yangdi Peng, Junyao Zhang, Yang Yang et al. · 0 citations

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