Global lessons from antibiotic resistance: metformin-hydrolyzing genes in transposable elements, a new threat for type II diabetic patients?
OBJECTIVES To investigate the evolutionary origin, genomic mobility, and potential dissemination of metformin-hydrolyzing genes (mfmAB), and to assess whether environmental selection by metformin pollution may drive the emergence of transferable pharmaceutical-degrading traits analogous to antibiotic resistance. METH...