Pieter-Jan De Sutter

Meropenem Dosing for Pediatric Critical Care Patients: Multisite Pharmacokinetic Study, 2012-2020.

OBJECTIVES Critically ill children may present with altered pharmacokinetics (PK) and/or pharmacodynamics (PD), leading to suboptimal dosing of meropenem. We aimed to: 1) investigate meropenem PK in critically ill children, 2) identify factors associated with interindividual PK variability, and 3) evaluate the PK/PD ta...