Author

Pietro Michiardi

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#machine learning Preprint Sep 2026

DRIFT: Disentangled Responsive-Invariant Flow Transport for Single-Cell Perturbation Prediction

Predicting cellular responses to perturbations is a central problem in cellular biology, with broad applications in systems biology and drug discovery. This task is challenging because cellular responses can be complex and cell-state dependent, intrinsic cell-to-cell variability can be confounded with perturbation effe...

Mustapha Bounoua, Giulio Franzese, Pietro Michiardi · 0 citations

#machine learning Preprint Sep 2026

ALICE: In-context, Zero-shot, Mutual Information Estimation

Estimating mutual information (MI) from samples is a central objective in a variety of scientific fields. Modern neural estimators are accurate in the large-data regime, but they fall short when data is scarce, and each must be fit anew for every distribution under study. Current estimators are moreover tied to specifi...

Giulio Franzese, Simone Rossi, Pietro Michiardi · 0 citations