Sep 2026
Cascade-Amplified Microfluidic Detection of Tumor Biomarkers via Metal-DNA Nanospheres Activating CRISPR-Cas12a Assay
The development of ultrasensitive protein detection platforms is pivotal for early cancer diagnosis, yet existing methods are often constrained by inefficient “protein-to-signal” conversion and complex instrumentation. While CRISPR-Cas-based biosensors offer higher sensitivity for nucleic acids, their application in...
Wen-Jian Zhao, Xiao-Wei Luan, Wen-Xiu Long et al.
· Analytical Chemistry · 0 citations