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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Ping-Jing Zhang

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Open access Oct 2026

Lipid-based mRNA chimeric antigen receptor T cells for enhanced in vitro antitumor activity

Summary Chimeric antigen receptor (CAR) T cell therapy provides substantial clinical benefits in hematologic malignancies. However, cell engineering using conventional viral vectors is costly, labor intensive, and prone to safety risks, while electroporation-induced cellular damage limits manufacturing scalability. Thi...

Hai-Xia Gao, Yuan Fang, Zhi-Dan Tian et al. · 0 citations
Review Open access Sep 2026

Advances in CAR-T Cell Therapy: From Structural Design Innovations to Clinical Translation Challenges

A comprehensive overview of the core advancements in CAR-T technology is provided, emphasizing the evolution of the five generations of CAR structures, and the latest innovations in transfection techniques are explored, highlighting optimizations and comparative advantages of viral and non-viral vectors.

Hai-Xia Gao, Yuan Fang, Ping-Jing Zhang et al. · 0 citations

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