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Open access Aug 2026

Integrative single-cell and bulk transcriptomic analyses identify a microglia-associated NAGLU signature linked to disulfidptosis-associated transcriptional patterns after spinal cord injury

Background Spinal cord injury (SCI) induces profound neuroinflammatory responses and extensive cellular remodeling within the injured spinal cord. Disulfidptosis, a recently identified form of regulated cell death associated with disulfide stress, has been implicated in cellular stress responses and tissue injury. Howe...

Xiao-Qin Liu, Jiating Hu, Wenxiao Zhu et al. · 0 citations
Open access Aug 2026

Defining the Early Response of Oligodendrocyte-Lineage Cells to Traumatic CNS Axonal Injury.

Injured central nervous system axons rarely regenerate or remyelinate efficiently. Oligodendrocyte (OL) -lineage cells influence both processes, yet their early response to axonal injury remains incompletely defined. Using an optic nerve crush model in male and female mice, we profiled acute OL-lineage responses over t...

Yu Wu, Xiaoyun Ding, Jiaxing Li et al. · 0 citations

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