Cycloechinulin inhibits breast cancer progression via the SGOL2/METTL3/ICAM2 signaling axis and suppresses the growth of breast cancer patient-derived organoids.
Breast cancer (BC) is a notoriously difficult malignancy to treat due to its high molecular heterogeneity and drug resistance. The vast structural diversity of marine-derived compounds remains underutilized in oncology drug development. This study investigates the anti-tumor potential and underlying molecular mechanism...