Open access
Oct 2026
RNA catalysis emerges from dynamic structural ensembles.
The dynamic interplay between RNA structure and its associated Mg2+ ions is central to RNA function yet remains poorly understood at a near-atomic level1-4. Here, using a heterogeneity-focused protocol for cryo-electron microscopy data analysis of conformationally flexible RNA particles, we determined the structures of...
M. Degenhardt, Hermann F. Degenhardt, Bapurao A. Bhoge et al.
· Nature · 0 citations