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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Po-Ren Hsueh

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3 papers indexed here

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Open access Oct 2026

Allele-specific GNB3 modulation of APOE ε4 memory effects

Modern environmental improvements have extended average lifespan, leading to increased prevalence of neurodegenerative diseases such as dementia. While memory decline is a natural physiological process of aging, numerous studies have demonstrated that certain genotypes increase the risk of cognitive decline and dementi...

Ling-Yi Xiao, Yang-Di Su, Chia-Yu Lin et al. · 0 citations
Open access Aug 2026

Maraviroc Inhibits SARS-CoV-2 Through Variant-Dependent Effects on Viral Entry and Mpro Activity Using Single-Round Infectious Particle and Virus-like Particle Models

It is demonstrated that MVC exerts variant-dependent antiviral effects by targeting viral entry, modulating trafficking pathways, and inhibiting Mpro activity against SARS-CoV-2 variants, providing insights into its potential therapeutic application.

U. Le, Po-Ju Chen, Li-Wei Chu et al. · 0 citations
Open access Aug 2026

Darunavir and Fosamprenavir Inhibit Zika Virus Replication via Dual Targeting of the Envelope Protein and NS2B–NS3 Protease

Zika virus (ZIKV) remains a significant global health concern, underscoring the need for effective antiviral agents. In this study, we evaluated the antiviral activity and mechanisms of the HIV protease inhibitors darunavir (DRV), fosamprenavir (FPV), and amprenavir (APV) against ZIKV. DRV and FPV, but not APV, exhibit...

Ju-Ying Kan, Hung-Chieh Su, Hsueh-Chou Lai et al. · 0 citations

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