The P2X7R-NLRP3 inflammasome axis in Alzheimer’s disease and therapeutic potential of synthetic and plant-derived natural compounds: A review
Alzheimer’s disease is a prevalent neurodegenerative disease that is characterized by synaptic dysfunction followed by neuronal loss. The core pathological mechanisms of Alzheimer’s disease include the extracellular deposition of amyloid beta (Αβ) plaques and intracellular neurofibrillary tangle deposits inside the b...