Author

P. M.R.

2 papers indexed here

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Review Sep 2026

Indole Derivatives in Modern Drug Discovery: A Comprehensive Review of their Pharmacological Potential and Synthetic Innovations

Due to its prevalence in endogenous biomolecules, natural products, and clinically approved medications, indole, a flexible bicyclic heterocycle, has become a crucial scaffold in contemporary medicinal chemistry. Recent developments in the synthesis, design, and pharmacological assessment of indole derivatives in a...

Shashank B, Pradeep Kumar Mr, Prateek A. Angadi · Current organic chemistry · 0 citations

Open access Jul 2026

DESIGN, SYNTHESIS, AND IN VITRO SCREENING OF MACROCYCLIC UREA-BASED HETEROCYCLIC SYSTEMS WITH UNUSUAL RING CONSTRAINTS

Macrocycles are highly privileged scaffolds in contemporary drug discovery, yet their inherent structural flexibility often imposes severe entropic penalties upon target binding. We report the rational design, synthesis, and comprehensive biological evaluation of a novel class of macrocyclic ureas that incorporate an u...

P. M.R., Palati Divya Jyothi, G. Hemalatha et al. · Genetics and Molecular Resea... · 0 citations