Neoadjuvant, adjuvant, and perioperative systemic therapy in urothelial cancers: Evolving paradigms and future directions
Radical surgery is the cornerstone of management for localized muscle-invasive urothelial carcinoma (MIUC), yet surgery alone cures only a proportion of patients because occult micrometastatic disease is common at diagnosis. Over the last two decades, perioperative systemic treatment has evolved from a cisplatin-based...