Evaluation of the antidepressant effect of Lactobacillus casei strain shirota in an ethanol-induced depression mouse model through behavioral, biochemical, neuroinflammatory, and histopathological assessment
Introduction: Depression is a complex neuropsychiatric disorder associated with behavioral abnormalities, neurotransmitter imbalance, oxidative stress, and neuroinflammation. Chronic alcohol exposure and withdrawal contribute to depressive-like behavior through disruption of neuronal function. The gut-brain axis has ga...