Praveen A. Kamble

Design, synthesis, mechanistic evaluation, and in silico study of pyrimidine-coumarin hybrids as promising anticancer agents.

Breast and lung cancers remain among the leading causes of cancer-related mortality worldwide, highlighting the urgent need for the development of effective targeted therapeutics. In this study, a series of novel pyrimidine-coumarin hybrid derivatives were rationally designed, synthesized, and biologically evaluated fo...