Preeti Jain

Innate immune dysregulation in celiac disease and refractory celiac disease: mechanisms, management and emerging therapies

Celiac disease is traditionally regarded as T-cell mediated autoimmune disorder driven by gluten-specific adaptive immune responses. In this review, we synthesise recent data showing how epithelial stress, IL-15 driven innate circuits and intraepithelial lymphocyte reprogramming contribute to both classical and refract...