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Author

Prem Shankar Gupta

2 papers indexed here

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Open access Oct 2026

Structure-activity relationship and molecular docking insights into newly synthesized Quinoline derivatives

Quinoline derivatives received much interest for the development of antidiabetic drugs because of to their diverse biological activities and structural flexibility. In this work, a novel series of quinoline based compounds were synthesised and characterised by different spectroscopic techniques. The structural modifica...

Ashwani Gaud, Prem Shankar Gupta · 0 citations
Review Aug 2026

Targeting BRAF dimerization in cancer: structural insights and therapeutic strategies beyond monomer inhibition.

The mitogen-activated protein kinase (MAPK) signaling pathway is a central oncogenic signaling axis, with BRAF functioning as a critical regulatory node. The discovery of oncogenic BRAF mutations, most notably BRAFV600E, enabled the development of targeted therapies that significantly improved clinical outcomes in seve...

Jayhind Bharti, Priyadharshini Gogu, Dhanashree N. Sarwan et al. · 0 citations

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