STEM CELL-DERIVED EXOSOMES: BIOGENESIS, CHARACTERIZATION, ISOLATION AND PRECONDITIONING
Introduction. Exosomes are nanoscale extracellular vesicles of endosomal origin (approximately 30–150 nm) secreted by almost all cell types, which mediate intercellular communication by carrying proteins, lipids and nucleic acids. Because stem cell-derived exosomes reproduce much of the paracrine activity of the parent...