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Author

Prince A. Dave

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Aug 2026

Design, synthesis and dual anticancer and antibacterial evaluation of novel 1,3,4-oxadiazole-2-thiol derivatives targeting EGFR and DNA Gyrase B: integrated docking, DFT and ADMET studies.

1,3,4-oxadiazole-2-thiol derivatives are established as promising dual-action therapeutic scaffolds for anticancer and antibacterial activities through computational and experimental approaches.

Ila M. Ram, Jay B. Maheta, Darshna K. Lakhnotra et al. · 0 citations
Aug 2026

Potential c-Met-targeted pyrazole-pyridine-oxadiazole hybrids: synthesis, anticancer activity, and computational rationale.

Findings identify 10d as a promising scaffold for further optimization and biological evaluation because it has the smallest HOMO-LUMO gap and highest chemical softness, consistent with its superior activity.

Prince A. Dave, Jay B. Maheta, Darshna K. Lakhnotra et al. · 0 citations

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