Open access
Sep 2026
Structural basis of the transport mechanism of hBGT1
In the kidney and liver, the betaine/γ-aminobutyric acid (GABA) transporter 1 (BGT1) transports betaine to maintain the osmotic balance of renal medullary cells and reduce the toxicity of homocysteine accumulation. In the brain, BGT1 reuptakes GABA from the synaptic cleft into glial cells to terminate GABAergic signali...
Kun Hao, Jia-Hui Chen, Jun Zhao et al.
· Cell Discovery · 0 citations