Heart failure (HF) affects 6.7 million people in the US and includes two major subtypes, HF with reduced ejection fraction (HFrEF) and HF with preserved ejection fraction (HFpEF), with distinct genetic architectures. We meta-analyze genome-wide association studies (GWAS) of 38,781 HFrEF cases, 38,163 HFpEF cases, and 5...
Chang Liu, Qin Hui, Gregorio V. Linchangco et al.· Nature Communications· 0 citations
Background/Objectives: Human immunodeficiency virus (HIV) infection is characterized by chronic systemic inflammation. Antiretroviral therapy (ART) can reduce persistent inflammation, as measured by C-reactive protein (CRP). The CRP methylation risk score (MRSCRP) acts as proxy for plasma CRP, but longitudinal changes...
Yi-Jie Huang, Junyu Chen, A. Young et al.· Epigenomes· 0 citations
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